Magdalena Pachota

Magdalena Pachota M.Sc.
PhD Student
Faculty of Biochemistry, Biophysics and Biotechnology
E-mail: magdalena.pachota [AT] uj.edu.pl

Research interests

  • Antiviral drugs

Supervisor(s)

prof Maria Nowakowska & prof Krzysztof Pyrc

Grants And Awards
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    • 2018. NCN Preludium. Novel inhibitors of herpes virus protease. PI: M Pachota.

    1. Synowiec A, Gryniuk I, Pachota M, Strzelec L, Roman O, Kłysik-Trzciańska K, Zając M, Drebot I, Gula K, Andruchowicz A, Rajfur Z, Szczubiałka K, Nowakowska K, Pyrc K. (2019). Cat flu: broad spectrum polymeric antivirals. Antiviral Research. in press.
    2. Pachota M, Kłysik-Trzciańska K, Synowiec A, Yukioka S, Yusa S, Zając, M, Zawilinska B, Dzieciątkowski T, Szczubiałka K, Pyrc K, Nowakowska M. (2019). Highly effective and safe polymeric inhibitors of herpes simplex virus in vitro and in vivo. ACS Applied Materials & Interfacesin press.
    3. Pachota M, Klysik K, Synowiec A, Ciejka J, Szczubialka K, Pyrc K, Nowakowska M. (2017) Inhibition of herpes simplex viruses by cationic dextran derivatives. Journal of Medicinal Chemistry. 60(20):8620-8630.
    4. Skalniak L, Zak K, Guzik K, Magiera K, Musielak B, Pachota M, Szelazek B, Kocik J, Grudnik P, Tomala M, Krzanik S, Pyrc K, Dömling A, Dubin G, Holak T. (2017) Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget. 8(42):72167-72181.
    5. Skorenski M, Pachota M, Pyrc K, Sienczyk M, Oleksyszyn J (2017) Novel Peptidyl α-Aminoalkylphosphonates as Inhibitors of Hepatitis C Virus NS3/4A Protease. Antiviral Research. 144:286-298.

    1. P. 416 749. The use of cationially modified dextran for the treatment of infections caused by HSV-1 virus.