Katarzyna Owczarek (Kosowicz), Ph.D.
Researcher
Laboratory of Virology MCB
E-mail: k.owczarek [AT] uj.edu.pl
Research interests
- Virus entry
Grants And Awards
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- 2018. NCN Preludium. Analysis of human coronavirus OC43 and Zika virus internalization routes in cells. Inhibition of the early steps of infection by intracellular pH tuning. PI: K Owczarek.
Publications
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- Synowiec A, Jedrysik M, Branicki W, Klajmon A, Lei J, Owczarek K, Chen S, Szczepanski A, Wang J, Zhang P, Labaj P, Pyrc K. (2021). Identification of cellular factors required for SARS-CoV-2 replication. Cells. in press.
- Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hoelscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Szczepanski A, Mohn KGI, Blomberg B, Sattler M*, Hadian K*, Popowicz GM*, Pyrc K*. Acriflavine, a clinically aproved drug, inhibits SARS-CoV-2 and other betacoronaviruses. Cell Chemical Biology. in press.
- Pancer K, Milewska A, Owczarek K, Dabrowska A, Kowalski M, Labaj P, Branicki W, Sanak M, Pyrc K. The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans. (2020). PLoS Pathogens. in press.
- Milewska A, Owczarek K, Szczepanski A, Pyrc K. Visualizing Coronavirus Entry into Cells. (2020) Methods in Molecular Biology. 2203:241-261.
- Milewska A, Kula-Pacurar A, Wadas J, Suder A, Szczepanski A, Dabrowska A, Owczarek K, Ochman M, Stacel T, Rajfur Z, Sanak M, Labaj P, Branicki W, Pyrc K. Replication of SARS-CoV-2 in human respiratory epithelium. (2020) Journal of Virology. doi: https://doi.org/10.1101/2020.03.20.999029
- Botwina P, Owczarek K, Rajfur Z, Ochman M, Urlik M, Nowakowska M, Szczubiałka K, Pyrc K. Berberine hampers influenza A replication through inhibition of MAPK/ERK pathway. (2020). Viruses. in press.
- Owczarek K, Chykunova Y, Jassoy C, Maksym B, Rajfur Z, Pyrc K. (2019) Zika virus: mapping and reprogramming the entry. (2019). Cell Communication and Signaling. 17(1):41.
- Szczepanski A, Owczarek K, Bzowska K, Gula K, Drebot I, Ochman M, Maksym B, Rajfur Z, Mitchell JA, Pyrc K. (2019) Canine Respiratory Coronavirus, Bovine Coronavirus and Human Coronavirus OC43: Receptors and attachment factors. Viruses. 11(4). pii: E328.
- Szczepanski A, Owczarek K, Milewska A, Baster Z, Rajfur Z, Mitchell J, Pyrc K. (2018) Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells. Veterinary Research. 49:55
- Owczarek K, Szczepanski A, Milewska A, Baster Z, Rajfur Z, Sarna M, Pyrc K. (2018) Early events during human coronavirus OC43 entry to the cell. Scientific Reports. 8(1):7124.
- A Milewska, P Nowak, K Owczarek, A Szczepanski, M Zarebski, A Hoang-Bujnowicz, K Berniak, J Wojarski, S Zeglen, Z Baster, Z Rajfur, K Pyrc (2017) Entry of human coronavirus NL63 to the cell. Journal of Virology. 92(3). pii: e01933-17.
- Milewska A, Kaminski K, Ciejka J, Kosowicz K, Zeglen S, Wojarski J, Nowakowska M, Szczubialka K¥, Pyrc K¥ (2016) HTCC: broad range inhibitor of coronavirus entry. PLoS One. 11(6):e0156552.